PICEATANNOL AMELIORATES CISPLATIN-INDUCED HISTOLOGICAL AND BIOCHEMICAL ALTERATIONS IN RATS KIDNEY

@article{Wahdan2017PICEATANNOLAC,
  title={PICEATANNOL AMELIORATES CISPLATIN-INDUCED HISTOLOGICAL AND BIOCHEMICAL ALTERATIONS IN RATS KIDNEY},
  author={Sara A. Wahdan and Samar S. Azab and Doaa A. El-Sherbiny and Ebtehal El-demerdash},
  journal={International Journal of Pharmacy and Pharmaceutical Sciences},
  year={2017},
  volume={9},
  pages={305-311}
}
Objective: The present study was designed to investigate the effect of different doses of piceatannol (PIC) on cisplatin-induced biochemical and histological alterations in rat kidney. Methods: Male Wistar rats received a single intraperitoneal (i. p.) injection of cisplatin (7 mg/kg). PIC was given in different daily doses (5, 10 and 20 mg/kg) i. p., for seven days, starting two days before cisplatin injection. Nephrotoxicity was evaluated by means of measurement of blood urea nitrogen (BUN… Expand

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