PI3Ks in lymphocyte signaling and development.

@article{Okkenhaug2010PI3KsIL,
  title={PI3Ks in lymphocyte signaling and development.},
  author={Klaus Okkenhaug and David A Fruman},
  journal={Current topics in microbiology and immunology},
  year={2010},
  volume={346},
  pages={57-85}
}
Lymphocyte development and function are regulated by tyrosine kinase and G-protein coupled receptors. Each of these classes of receptors activates phosphoinositide 3-kinase (PI3K). In this chapter, we summarize current understanding of how PI3K contributes to key aspects of the adaptive immune system.