PI 3 K-mTORC 1 Attenuates Stress Response by Inhibiting Cap-independent Hsp 70 Translation *

@inproceedings{Sun2011PI3K,
  title={PI 3 K-mTORC 1 Attenuates Stress Response by Inhibiting Cap-independent Hsp 70 Translation *},
  author={Jun Sun and Crystal S Conn and Yan Han and Vincent Yeung and Shu-Bing Qian},
  year={2011}
}
Protein synthesis is a key regulated cellular process that links nutrient availability and organismal growth. It has long been known that some cellular proteins continue to be synthesized under conditions where global translation is severely compromised. One prominent example is the selective translation of heat shock proteins (Hsps) under stress conditions. Although the transcriptional regulation ofHsp genes has been well established, neither the specific translation-promoting features nor the… CONTINUE READING
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