PHF21B as a candidate tumor suppressor gene in head and neck squamous cell carcinomas.


A significant association between DNA losses on 22q13.31 and head and neck squamous cell carcinomas (HNSCC) was previously reported by our group. Our data indicated that PHF21B gene, mapped on 22q13.31 and encoding a protein with function of chromatin-mediated transcriptional regulation, might be a putative tumor suppressor gene. To test this hypothesis… (More)
DOI: 10.1016/j.molonc.2014.09.009


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