PHENAZOCINE, A NEW BENZOMORPHAN NARCOTIC ANALGESIC

@article{Eckenhoff1959PHENAZOCINEAN,
  title={PHENAZOCINE, A NEW BENZOMORPHAN NARCOTIC ANALGESIC},
  author={JAMES E. Eckenhoff},
  journal={Anesthesiology},
  year={1959},
  volume={20},
  pages={355–358}
}
Pentazocine and phenazocine. A double-blind comparison of two benzomorphan derivatives in postoperative pain.
TLDR
Changes in vital capacity gave a good indication of postoperative pain relief after both upper and lower abdominal operations, and changes were found to be significantly correlated with vital capacity before injection.
To our readers: an experiment in education.
TLDR
The purpose of this editorial is to describe changes in presentation of research and new educational content beginning with this issue of the journal designed to better disseminate the new knowledge that the authors publish.
About Our Authors
TLDR
In this editorial, the Editorial Board of ANESTHESIOLOGY reviews what it thinks it knows about authors’ needs and desires and how it is trying to better meet them, and aims to increase reviewers from Australasia and Europe.
Curareähnliche oder neuromuskulär blockierende Pharmaka
Pharmaka, die die Skeletmuskulatur lahmen, werden vorwiegend wahrend der Anaesthesie verwendet. Die Pharmakologie dieser Pharmaka wurde teilweise schon in fruheren Kapiteln im Zusammenhang mit
Studies of drugs given before anaesthesia. 13. Pentazocine and other opiate antagonists.
TLDR
The non-addicting analgesic pentazocine (Fortral) was compared with the established opiate antagonists nalorphine and levallorphan when used in pre-operative medication in female patients and the antagonists were all less toxic than the addicting opiates, though all were worse than saline.
CATARACT EXTRACTION UNDER COMBINED LOCAL AND GENERAL ANALGESIA USING PHENAZOCINE*
THE recent introduction of a powerful general analgesic drug, phenazocine (" Narphen"), with a potency stated to be seven to ten times that of morphine (Eckenhoff, 1959) has enabled us to make use of
Laboratory and clinical experience with phenazocine during anaesthesia
TLDR
Phenazocine does not possess the histamine-releasing properties associated with meperidine, but is capable of inducing a reduction of the respiratory rate in animals and in man.
ANALGESIA AND ADDICTION.
  • L. MellettL. A. Woods
  • Medicine
    Fortschritte der Arzneimittelforschung. Progress in drug research. Progres des recherches pharmaceutiques
  • 1963
TLDR
It is an unfortunate fact that the potent drugs which produce analgesia are concomitantly addicting, i.e. that they produce physical and psychic dependence as well as exhibiting the phenomenon of tolerance development.
Clinical pharmacology of potent analgesics
TLDR
The object of this review is to summarize the current knowledge of morphine and morphinelike drugs and to suggest that if used wisely, morphine, the oldest agent, is still one of the best.
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