PHARMACOLOGY OF METOPON AND OTHER NEW ANALGESIC OPIUM DERIVATIVES

@article{Eddy1948PHARMACOLOGYOM,
  title={PHARMACOLOGY OF METOPON AND OTHER NEW ANALGESIC OPIUM DERIVATIVES},
  author={Nathan B. Eddy},
  journal={Annals of the New York Academy of Sciences},
  year={1948},
  volume={51}
}
  • N. B. Eddy
  • Published 1 November 1948
  • Chemistry
  • Annals of the New York Academy of Sciences
Development of 5-Substituted N-Methylmorphinan-6-ones as Potent Opioid Analgesics with Improved Side-Effect Profile
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14-alkoxy-N-methylmorphinan-6-ones having a methyl and benzyl group at position 5 are reported on as strong opioid antinociceptive agents with reduced propensity to cause undesired effects compared to morphine although interacting selectively with MORs.
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The pharmacological profile of Kop agonists in visceral pain models suggest that peripherally restricted KOP agonists are potentially useful for a variety of peripheral pain states.
Clinical pharmacology of potent analgesics
TLDR
The object of this review is to summarize the current knowledge of morphine and morphinelike drugs and to suggest that if used wisely, morphine, the oldest agent, is still one of the best.
A STEREOTYPED RESPONSE INDUCED BY MESCALINE IN MICE AS A MEANS OF INVESTIGATING THE PROPERTIES OF DRUGS ACTING ON THE CNS
TLDR
The effects of mescaline on spontaneous activity of mice placed in special cages have been studied and the typical response has been recorded and assessed in terms of percentage of animals showing the effect.
The chemistry of drugs of addiction.
  • E. May
  • Chemistry
    The American journal of medicine
  • 1953
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