Corpus ID: 220618443

PHARMACEUTICAL COCRYSTAL OF PRULIFLOXACIN WITH NICOTINAMIDE

@article{Morampudi2014PHARMACEUTICALCO,
  title={PHARMACEUTICAL COCRYSTAL OF PRULIFLOXACIN WITH NICOTINAMIDE},
  author={Raghuram Morampudi and Sarwar Alam Mohammad and M. Prasad and Chandra Has Khanduri},
  journal={International Journal of Pharmacy and Pharmaceutical Sciences},
  year={2014},
  volume={6},
  pages={180-184}
}
Objective: Cocrystals have been increasingly recognized as an attractive alternative for solid forms of drug products. In this work nicotinamide (NCT) was employed to form the cocrystal with the active pharmaceutical ingredient prulifloxacin (PF). Methods: The PF-NCT cocrystal was prepared by employing slow evaporation and solution crystallization methodology from acetone as a solvent. The PF-NCT cocrystal was characterized by powder X-ray diffraction (PXRD), infrared (IR) spectroscopy, raman… Expand
2 Citations

References

SHOWING 1-10 OF 14 REFERENCES
Solubility Advantage of Pharmaceutical Cocrystals
  • 490
Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates.
  • 1,007
  • PDF
Pharmaceutical Cocrystals and Their Physicochemical Properties
  • 938
[In vitro antibacterial activity of prulifloxacin, a new oral fluoroquinolone].
  • 6
Improving drug solubility for oral delivery using solid dispersions.
  • C. Leuner, J. Dressman
  • Materials Science, Medicine
  • European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
  • 2000
  • 2,434
Oral lipid-based formulations.
  • D. Hauss
  • Chemistry, Medicine
  • Advanced drug delivery reviews
  • 2007
  • 459
...
1
2
...