PGI2 production by rat blood vessels: diminished prostacyclin formation in veins compared to arteries.


Homogenates of eleven different blood vessels from normal Sprague-Dawley rats varied in their ability to produce PGI2 (i.e., 6-keto-PGF1 alpha) from [1-14C]PGH2. The most notable difference was seen between arteries and veins. Arterial tissues produced more 6-keto-PGF1alpha from exogenous PGH2 than veins at all enzyme (i.e., protein) concentrations tested… (More)


  • Presentations referencing similar topics