PGE2 suppresses intestinal T cell function in thermal injury: a cause of enhanced bacterial translocation.

@article{Choudhry2001PGE2SI,
  title={PGE2 suppresses intestinal T cell function in thermal injury: a cause of enhanced bacterial translocation.},
  author={Mashkoor A. Choudhry and Nadeem Fazal and Shahla Y Namak and Farah N Haque and Thyyar M Ravindranath and M. M. Alamgir Sayeed},
  journal={Shock},
  year={2001},
  volume={16 3},
  pages={183-8}
}
Increased gut bacterial translocation in burn and trauma patients has been demonstrated in a number of previous studies, however, the mechanism for such an increased gut bacterial translocation in injured patients remains poorly understood. Utilizing a rat model of burn injury, in the present study we examined the role of intestinal immune defense by analyzing the T cell functions. We investigated if intestinal T cells dysfunction contributes to bacterial translocation after burn injury. Also… CONTINUE READING
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