PGE from Octopus aegina Induces Apoptosis in Ehrlich's Ascites Carcinoma of Mice.

@article{Karthigayan2007PGEFO,
  title={PGE from Octopus aegina Induces Apoptosis in Ehrlich's Ascites Carcinoma of Mice.},
  author={S. Karthigayan and Muralimanoharan Sri Balasubashini and Thangavel Balasubramanian and S. T. Somasundaram},
  journal={Toxicology mechanisms and methods},
  year={2007},
  volume={17 8},
  pages={451-8}
}
ABSTRACT The present study was carried out to assess the antitumor effect of venomous peptide from the cephalopod Octopus aegina on Ehrlich's ascites carcinoma (EAC). Male albino Swiss mice were used in the present study. Four groups of animals were treated with three doses of the sublethal dose of venom, 15, 75, and 150 mug/kg body weight (intraperitoneal injection), along with the standard drug 5-fluorouracil (20 mg/kg b.w.). After 10 days of treatment, six animals from each group were… CONTINUE READING