PGD2 is an intermediate in agonist-stimulated nitric oxide release in rabbit skin microcirculation.

@article{Warren1994PGD2IA,
  title={PGD2 is an intermediate in agonist-stimulated nitric oxide release in rabbit skin microcirculation.},
  author={John B Warren and Roberto Loi and Annabel J Wilson},
  journal={The American journal of physiology},
  year={1994},
  volume={266 5 Pt 2},
  pages={H1846-53}
}
We investigated the role of endogenous prostaglandins and NO in the blood flow response of skin microcirculation in vivo. Test agents were injected intradermally in anesthetized rabbits and changes in skin blood flow measured with a laser-Doppler flow probe. Skin blood flow increased 75% at 7.33, 6.77, 11.63, 10.30, 10.55, 8.20, and < 7 -log mol/site with… CONTINUE READING