PGD analysis for aneuploidy in a patient heterozygous for a polymorphism of chromosome 16 (16qh-).

@article{Colls2004PGDAF,
  title={PGD analysis for aneuploidy in a patient heterozygous for a polymorphism of chromosome 16 (16qh-).},
  author={Pere Colls and Mireia Sandalinas and Kelly Pagidas and Santiago Munn{\'e}},
  journal={Prenatal diagnosis},
  year={2004},
  volume={24 9},
  pages={741-4}
}
OBJECTIVES Detection and study of a polymorphism of chromosome 16qh in preimplantational embryos as well as in peripheral blood from the carrier. METHODS A polymorphism of chromosome 16 (16qh-) was detected in PGD analysis for aneuploidy using a probe for the centromeric region of chromosome 16. The lack of pericentromeric heterochromatin in one of the chromosomes 16 could lead to misdiagnosis in PGD. PGD analysis using telomeric probes for this chromosome was performed to confirm the… CONTINUE READING