PGC-1alpha Gly482Ser polymorphism is associated with the plasma adiponectin level in type 2 diabetic men.

@article{Okauchi2008PGC1alphaGP,
  title={PGC-1alpha Gly482Ser polymorphism is associated with the plasma adiponectin level in type 2 diabetic men.},
  author={Yukiyoshi Okauchi and Hiromi Iwahashi and Kohei Okita and Ming Yuan and Morihiro Matsuda and Toshiya Tanaka and Junichiro Miyagawa and Tohru Funahashi and Yukio Horikawa and Iichiro Shimomura and Kazuya Yamagata},
  journal={Endocrine journal},
  year={2008},
  volume={55 6},
  pages={991-7}
}
Peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1alpha) is a multifunctional transcriptional regulator for the pathways controlling mitochondrial biogenesis, oxidative metabolism, and glucose homeostasis. Genetic studies have suggested that Gly482Ser polymorphism of the PGC-1alpha gene is associated with a higher risk of type 2 diabetes, obesity, and hypertension. Adiponectin is an antidiabetic and antiatherogenic adipocytokine that is specifically produced by adipose… CONTINUE READING
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