PGC-1α and exercise in the control of body weight

@article{Summermatter2012PGC1AE,
  title={PGC-1$\alpha$ and exercise in the control of body weight},
  author={Serge Summermatter and Christoph Handschin},
  journal={International Journal of Obesity},
  year={2012},
  volume={36},
  pages={1428-1435}
}
The increasing prevalence of obesity and its comorbidities represents a major threat to human health globally. Pharmacological treatments exist to achieve weight loss, but the subsequent weight maintenance is prone to fail in the long run. Accordingly, efficient new strategies to persistently control body weight need to be elaborated. Exercise and dietary interventions constitute classical approaches to reduce and maintain body weight, yet people suffering from metabolic diseases are often… 
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