PGAIPG, a repeated hexapeptide of bovine and human tropoelastin, is chemotactic for neutrophils and Lewis lung carcinoma cells.

@article{Grosso1993PGAIPGAR,
  title={PGAIPG, a repeated hexapeptide of bovine and human tropoelastin, is chemotactic for neutrophils and Lewis lung carcinoma cells.},
  author={Leonard E. Grosso and M Scott},
  journal={Archives of biochemistry and biophysics},
  year={1993},
  volume={305 2},
  pages={
          401-4
        }
}
Fetal bovine ligamentum nuchae fibroblasts express a 67-kDa, lactose-sensitive receptor that binds to VGVAPG, a repeated hexapeptide, of bovine and human tropoelastin. Recently, studies utilizing recombinant tropoelastin deletion proteins in conjunction with synthetic peptides identified a second fibroblast receptor binding site, PGAIPG. To evaluate whether PGAIPG is a ligand for elastin receptors of other cells, the chemotactic response of neutrophils and Lewis lung carcinoma tumor cells (M27… CONTINUE READING

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