PGA4, a GAS homologue from Candida albicans, is up-regulated early in infection processes.

@article{Eckert2007PGA4AG,
  title={PGA4, a GAS homologue from Candida albicans, is up-regulated early in infection processes.},
  author={Sabine E. Eckert and Werner J. Heinz and Katherina Zakikhany and Sascha Thewes and Ken Haynes and Bernhard Hube and Fritz A. M{\"u}hlschlegel},
  journal={Fungal genetics and biology : FG & B},
  year={2007},
  volume={44 5},
  pages={368-77}
}
Transglucosidases play a significant role in fungal cell wall biosynthesis. We identified three as yet undescribed genes encoding beta-glucan transglucosidases, homologues of the pH-regulated PHR1 and PHR2, in the genome of the pathogenic yeast Candida albicans. Transcript levels of the gene PGA4 encoding a putative GPI-anchored protein were elevated in C. albicans wild-type cells during infection of reconstituted human epithelial and mouse liver tissue, and transiently increased after… CONTINUE READING

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