PET studies of parkinsonism associated with mutation in the alpha-synuclein gene.


OBJECTIVE To assess the pattern of dopaminergic abnormalities in a Greek-American kindred (family H) with autosomal dominantly inherited, levodopa-responsive parkinsonism caused by a mutation of the gene encoding alpha-synuclein. BACKGROUND Mutations of alpha-synuclein have been associated recently with dominantly inherited, levodopa-responsive… (More)


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