PET scanning of iodine-124-3F9 as an approach to tumor dosimetry during treatment planning for radioimmunotherapy in a child with neuroblastoma.

@article{Larson1992PETSO,
  title={PET scanning of iodine-124-3F9 as an approach to tumor dosimetry during treatment planning for radioimmunotherapy in a child with neuroblastoma.},
  author={Steven M. Larson and Keith S. Pentlow and Nora D. Volkow and Alfred P. Wolf and Ronald D. Finn and Richard M. Lambrecht and Martin C. Graham and G Di Resta and Bernard Bendriem and Farhad Daghighian},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={1992},
  volume={33 11},
  pages={2020-3}
}
A patient with advanced neuroblastoma who had failed chemotherapy presented with a large abdominal mass and virtually total bone marrow replacement by tumor on repeated marrow biopsies. She was considered a candidate for a Phase I 131I-3F8 radioimmunotherapy trial, (MSKCC 89-141A). As a potential aid to treatment planning, a test dose of 124I-3F8 was injected and the patient was imaged over the 72 hr postinjection using two BGO based PET scanners of different designs. Time activity curves were… CONTINUE READING