PET quantification of 5-HT2A receptors in the human brain: a constant infusion paradigm with [18F]altanserin.

@article{Dyck2000PETQO,
  title={PET quantification of 5-HT2A receptors in the human brain: a constant infusion paradigm with [18F]altanserin.},
  author={Christopher H. van Dyck and Pinar Z. Tan and Ronald M. Baldwin and Louis Amici and Pradeep K Garg and Chin Kau Ng and Robert Soufer and Dennis S. Charney and Robert B. Innis},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2000},
  volume={41 2},
  pages={234-41}
}
UNLABELLED [18F]altanserin has been used to label serotonin 5-HT2A receptors, which are believed to be important in the pathophysiology of schizophrenia and depression. The purpose of this study was to test the feasibility of a constant infusion paradigm for equilibrium modeling of [18F]altanserin with PET. Kinetic modeling with [18F]altanserin may be… CONTINUE READING