PET of glucagonlike peptide receptor upregulation after myocardial ischemia or reperfusion injury.

@article{Gao2012PETOG,
  title={PET of glucagonlike peptide receptor upregulation after myocardial ischemia or reperfusion injury.},
  author={Haokao Gao and Dale O. Kiesewetter and Xiaoxiang Zhang and Xinglu Huang and Ning Guo and Lixin Lang and Naoki Hida and Hui Wang and Haichang Wang and Feng Yi Cao and Gang Niu and Xiaoyuan Chen},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2012},
  volume={53 12},
  pages={1960-8}
}
UNLABELLED Glucagonlike peptide (GLP-1) and its receptor (GLP-1R) exhibit cardioprotective effects after myocardial ischemia and reperfusion (MI/R) in both animal studies and clinical trials. However, the kinetics of GLP-1R expression in the infarcted/ischemic myocardium has not yet been explored. The purpose of this study was to monitor the presence and time course of regional myocardial GLP-1R expression after MI/R with noninvasive PET. METHODS Male Sprague-Dawley rats underwent a 45-min… CONTINUE READING
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