PET imaging of dopamine receptors in human basal ganglia: relevance to mental illness

@article{Sedvall1990PETIO,
  title={PET imaging of dopamine receptors in human basal ganglia: relevance to mental illness},
  author={G{\"o}ran Sedvall},
  journal={Trends in Neurosciences},
  year={1990},
  volume={13},
  pages={302-308}
}
  • Göran Sedvall
  • Published in Trends in Neurosciences 1990
  • Psychology, Medicine
  • The development of PET and in vivo ligand-binding techniques over the past decade has allowed the analysis of dopamine receptor functions in the basal ganglia of human subjects. Using ligands selective for the different subtypes of dopamine receptors, their gross distribution, total number of binding sites and affinity have been determined in the caudate-putamen of the living human brain. Recent studies in young, drug-naive schizophrenic patients failed to demonstrate a consistent alteration in… CONTINUE READING

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