PET and MRI reveal early evidence of neurodegeneration in spinocerebellar ataxia type 17.

@article{Brockmann2012PETAM,
  title={PET and MRI reveal early evidence of neurodegeneration in spinocerebellar ataxia type 17.},
  author={Kathrin Brockmann and Matthias Reimold and Christoph Globas and Till Karsten Hauser and Uwe Walter and Hans-J{\"u}rgen Machulla and Arndt Rolfs and Ludger Sch{\"o}ls},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2012},
  volume={53 7},
  pages={1074-80}
}
UNLABELLED Spinocerebellar ataxia type 17 (SCA17) is a rare autosomal dominantly inherited neurodegenerative disorder presenting with a variable phenotype including ataxia, dystonia, chorea, and parkinsonism, as well as cognitive impairment. We evaluated morphologic and functional imaging characteristics to elucidate evidence of neurodegeneration in SCA17, even in the presymptomatic stage of the disease. METHODS Nine individuals of 3 large SCA17 pedigrees, including 4 presymptomatic mutation… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 5 times over the past 90 days. VIEW TWEETS