PERIOD–TIMELESS Interval Timer May Require an Additional Feedback Loop

@article{Kuczenski2007PERIODTIMELESSIT,
  title={PERIOD–TIMELESS Interval Timer May Require an Additional Feedback Loop},
  author={Robert S. Kuczenski and Kevin C. Hong and Jordi Garc{\'i}a-Ojalvo and Kelvin H. Lee},
  journal={PLoS Computational Biology},
  year={2007},
  volume={3},
  pages={673 - 678}
}
In this study we present a detailed, mechanism-based mathematical framework of Drosophila circadian rhythms. This framework facilitates a more systematic approach to understanding circadian rhythms using a comprehensive representation of the network underlying this phenomenon. The possible mechanisms underlying the cytoplasmic "interval timer" created by… CONTINUE READING