PEPOP: Computational design of immunogenic peptides

Abstract

Most methods available to predict protein epitopes are sequence based. There is a need for methods using 3D information for prediction of discontinuous epitopes and derived immunogenic peptides. PEPOP uses the 3D coordinates of a protein both to predict clusters of surface accessible segments that might correspond to epitopes and to design peptides to be… (More)
DOI: 10.1186/1471-2105-9-71

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