PEGylation does not impair insulin efficacy in three-dimensional cartilage culture: an investigation toward biomimetic polymers.

Abstract

A major goal in tissue engineering is the controlled application of growth factors. As a novel application system, we are currently developing biomimetic polymers that are processed into three-dimensional scaffolds. Bioactive proteins will be covalently bound to the polymers via a poly(ethylene glycol) (PEG) linker. Of paramount importance is the… (More)

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