PEG-embedded KBr3: A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines

Abstract

PEG-embedded potassium tribromide ([K(+)PEG]Br(3) (-)) was found to be an efficient and recyclable catalyst for the synthesis of functionalized piperidines in high yields in a one step, three component coupling between aldehyde, amine and β-keto ester. At the end of the reaction the [K(+)PEG]Br(3) (-) was readily regenerated from the reaction mixture by… (More)
DOI: 10.3762/bjoc.7.157

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