PEDIATRIC PHARMACOTHERAPY A Monthly Newsletter for Health Care Professionals from the University of Virginia Children ’ s Hospital Volume 12 Number 10 October 2006 Use of Aminocaproic Acid in Children Undergoing Cardiac Surgery or ECMO

@inproceedings{Buck2006PEDIATRICPA,
  title={PEDIATRIC PHARMACOTHERAPY A Monthly Newsletter for Health Care Professionals from the University of Virginia Children ’ s Hospital Volume 12 Number 10 October 2006 Use of Aminocaproic Acid in Children Undergoing Cardiac Surgery or ECMO},
  author={Marcia L. Buck},
  year={2006}
}
ntifibrinolytics, such as aprotinin, aminocaproic acid (ACA), and tranexamic acid, are used intraoperatively, postoperatively, and during extracorporeal membrane oxygenation (ECMO) to reduce bleeding and minimize the need for exogenous blood products. While aprotinin has been the most extensively studied, its use declined sharply after publication of a multicenter observational study comparing it with ACA, tranexamic acid, and placebo in 4,374 adults which revealed an increased risk of renal… CONTINUE READING
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