PEDF and the serpins: phylogeny, sequence conservation, and functional domains.

Abstract

Pigment epithelium derived factor (PEDF) is non-inhibitory serpin with neurotrophic and antiangiogenic functions. In this study, we have assembled PEDF sequences for 9 additional species by data base mining and performed cross-species alignment for 14 PEDF sequences to identify conserved structural domains. We found evolutionary conservation of a leader… (More)

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Cite this paper

@article{TombranTink2005PEDFAT, title={PEDF and the serpins: phylogeny, sequence conservation, and functional domains.}, author={Joyce Tombran-Tink and Samuel Aparicio and Xuming Xu and Amber R Tink and N{\'u}ria Lara and Supriya Sawant and Colin J Barnstable and Samuel Shao-Min Zhang}, journal={Journal of structural biology}, year={2005}, volume={151 2}, pages={130-50} }