PECAM-1 is necessary for flow-induced vascular remodeling.

@article{Chen2009PECAM1IN,
  title={PECAM-1 is necessary for flow-induced vascular remodeling.},
  author={Zhongming Chen and Ellie Tzima},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2009},
  volume={29 7},
  pages={1067-73}
}
OBJECTIVE Vascular remodeling is a physiological process that occurs in response to long-term changes in hemodynamic conditions, but may also contribute to the pathophysiology of intima-media thickening (IMT) and vascular disease. Shear stress detection by the endothelium is thought to be an important determinant of vascular remodeling. Previous work showed that platelet endothelial cell adhesion molecule-1 (PECAM-1) is a component of a mechanosensory complex that mediates endothelial cell (EC… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 36 extracted citations

Endothelial Mechanosignaling: Does One Sensor Fit All?

Antioxidants & redox signaling • 2016
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 49 references

Similar Papers

Loading similar papers…