PECAM‐1, a key player in neuroinflammation

@article{Kalinowska2006PECAM1AK,
  title={PECAM‐1, a key player in neuroinflammation},
  author={Alicja Kalinowska and Jacek Losy},
  journal={European Journal of Neurology},
  year={2006},
  volume={13}
}
Platelet endothelial cell adhesion molecule‐1 (PECAM‐1, CD31) is a 130‐kDa protein, which plays a significant role in the adhesion cascade. It is therefore involved in leucocyte endothelium interaction and in leucocyte transendothelial migration during inflammation. As neuroinflammation and subsequent blood brain barrier disruption are integral processes in many neurological disorders, PECAM‐1 and its soluble form (sPECAM‐1) have been investigated in a number of conditions, rising hopes as a… Expand
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