PEA3 transactivates the Muc4/sialomucin complex promoter in mammary epithelial and tumor cells.

Abstract

Sialomucin complex (SMC, rat Muc4) is a heterodimeric glycoprotein composed of two subunits, the mucin component ascites sialoglycoprotein ASGP-1 and the transmembrane subunit ASGP-2, which is aberrantly expressed on the surfaces of a variety of tumor cells. Up-regulation of the Muc4/SMC gene in the 13762 sublines of the rat mammary adenocarcinoma… (More)

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@article{Perez2003PEA3TT, title={PEA3 transactivates the Muc4/sialomucin complex promoter in mammary epithelial and tumor cells.}, author={Aymee Perez and Roy Barco and Isabel Fernandez and Shari A. Price-Schiavi and Kermit L. Carraway}, journal={The Journal of biological chemistry}, year={2003}, volume={278 38}, pages={36942-52} }