PE-CVD processes improve cell affinity of polymer scaffolds for tissue engineering

@inproceedings{Intranuovo2011PECVDPI,
  title={PE-CVD processes improve cell affinity of polymer scaffolds for tissue engineering},
  author={Francesca Intranuovo and Eloisa Sardella and Roberto Gristina and Marina Nardulli and Lisa J White and Daniel Howard and Kevin M. Shakesheff and Morgan R Alexander and Pietro Favia},
  year={2011}
}
Abstract Poly e-caprolactone (PCL) and poly D,L -lactic acid (P D,L LA) scaffolds with controlled pore dimensions (100–200 μm) were processed in low pressure RF (13.56 MHz) Glow Discharges. Ethylene/N 2 mixtures (for PCL) and allyl amine (for P D,L LA) were used to plasma deposit cell-adhesive coatings with controlled conditions to increase the affinity of Saos2 osteoblast and 3T3 fibroblast cell lines, respectively. Very promising results were obtained in terms of N-containing species… CONTINUE READING