PDX-1, CDX-2, TTF-1, and CK7: a reliable immunohistochemical panel for pancreatic neuroendocrine neoplasms.

Abstract

Neuroendocrine tumors (NETs) occur in virtually all sites of the body. As NETs arising in different organs share similar morphologic features, distinguishing metastatic from primary NETs on the basis of morphologic grounds alone is difficult. Pancreatic duodenal homeobox 1 (PDX-1) is a Hox-type transcription factor that is essential for both exocrine and… (More)
DOI: 10.1097/PAS.0b013e31824aba59

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Cite this paper

@article{Chan2012PDX1CT, title={PDX-1, CDX-2, TTF-1, and CK7: a reliable immunohistochemical panel for pancreatic neuroendocrine neoplasms.}, author={Elaine W S Chan and Jacob Alexander and Paul E. Swanson and D. S. Jain and Matthew M Yeh}, journal={The American journal of surgical pathology}, year={2012}, volume={36 5}, pages={737-43} }