PDGF stimulates the massive expansion of glial progenitors in the neonatal forebrain.

Abstract

Platelet-derived growth factor (PDGF) plays a major role in regulating migration, proliferation, and differentiation of glial progenitors during normal brain development and in the abnormal proliferation and dispersion that drives the formation of malignant gliomas. To further explore the relationship between PDGF's effects on normal glial progenitors and… (More)
DOI: 10.1002/glia.20895

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