PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection


Here, we report on the expression of programmed death (PD)-1 on human virus-specific CD8(+) T cells and the effect of manipulating signaling through PD-1 on the survival, proliferation, and cytokine function of these cells. PD-1 expression was found to be low on naive CD8(+) T cells and increased on memory CD8(+) T cells according to antigen specificity… (More)

5 Figures and Tables


  • Presentations referencing similar topics