PD-1/PD-L1 expression in human T-cell leukemia virus type 1 carriers and adult T-cell leukemia/lymphoma patients

@article{Kozako2009PD1PDL1EI,
  title={PD-1/PD-L1 expression in human T-cell leukemia virus type 1 carriers and adult T-cell leukemia/lymphoma patients},
  author={Tomohiro Kozako and Makoto Yoshimitsu and Hitoshi Fujiwara and Izumi Masamoto and Sawako Horai and Yohann White and Masaki Akimoto and Shinsuke Suzuki and Kakushi Matsushita and Kimiharu Uozumi and Chuwa Tei and Naomichi Arima},
  journal={Leukemia},
  year={2009},
  volume={23},
  pages={375-382}
}
Adult T-cell leukemia/lymphoma (ATLL) develops after infection with human T-cell leukemia virus-1 (HTLV-1) after a long latency period. The negative regulatory programmed death-1/programmed death-1 ligand 1 (PD-1/PD-L1) pathway has been implicated in the induction of cytotoxic T-lymphocyte (CTL) exhaustion during chronic viral infection along with tumor escape from host immunity. To determine whether the PD-1/PD-L1 pathway could be involved in the establishment of persistent HTLV-1 infections… CONTINUE READING
79 Citations
49 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 79 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 49 references

CHOP for adult T-cell leukemia-lymphoma: Japan Clinical Oncology Group Study JCOG9801

  • Y Yamada, M Tomonaga, H Fukuda, S Hanada, A Utsunomiya, M Tara
  • J Clin Oncol
  • 2007

Similar Papers

Loading similar papers…