PCR mapping of integrons reveals several novel combinations of resistance genes.

  title={PCR mapping of integrons reveals several novel combinations of resistance genes.},
  author={C{\'e}line L{\'e}vesque and Lyson Pich{\'e} and C Larose and Paul H. Roy},
  journal={Antimicrobial agents and chemotherapy},
  volume={39 1},
The integron is a new type of mobile element which has evolved by a site-specific recombinational mechanism. Integrons consist of two conserved segments of DNA separated by a variable region containing one or more genes integrated as cassettes. Oligonucleotide probes specific for the conserved segments have revealed that integrons are widespread in recently isolated clinical bacteria. Also, by using oligonucleotide probes for several antibiotic resistance genes, we have found novel combinations… CONTINUE READING
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