PCR in laboratory diagnosis of human Borrelia burgdorferi infections.

  title={PCR in laboratory diagnosis of human Borrelia burgdorferi infections.},
  author={Bruno L Schmidt},
  journal={Clinical microbiology reviews},
  volume={10 1},
The laboratory diagnosis of Lyme borreliosis, the most prevalent vector-borne disease in the United States and endemic in parts of Europe and Asia, is currently based on serology with known limitations. Direct demonstration of Borrelia burgdorferi by culture may require weeks, while enzyme-linked immunosorbent assays for antigen detection often lack sensitivity. The development of the PCR has offered a new dimension in the diagnosis. Capable of amplifying minute amounts of DNA into billions of… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 54 extracted citations

Promising alternatives for one-tier testing of Lyme borreliosis.

Clinica chimica acta; international journal of clinical chemistry • 2018
View 7 Excerpts
Highly Influenced

Diagnosis of lyme borreliosis.

Clinical microbiology reviews • 2005
View 4 Excerpts
Highly Influenced

History of Morgellons disease: from delusion to definition

Clinical, cosmetic and investigational dermatology • 2018
View 1 Excerpt

Morgellons disease: a filamentous borrelial dermatitis

International journal of general medicine • 2016
View 3 Excerpts

Similar Papers

Loading similar papers…