PCR-based microsatellite polymorphisms in the detection of loss of heterozygosity in fresh and archival tumour tissue.

Abstract

PCR-based microsatellite polymorphisms have proved their power in genetic linkage analysis and other identification methods, due to their high information content and even distribution over the chromosomes. In the present study we applied microsatellite polymorphisms to detect loss of heterozygosity in fresh (snap-frozen) and in archival ovarian tumour… (More)
DOI: 10.1038/bjc.1993.333

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@article{Gruis1993PCRbasedMP, title={PCR-based microsatellite polymorphisms in the detection of loss of heterozygosity in fresh and archival tumour tissue.}, author={Nelleke A. Gruis and Edwin C. A. Abeln and Alfons F J Bardoel and Peter Devilee and Regina Frants and Cees J. Cornelisse}, journal={British Journal of Cancer}, year={1993}, volume={68}, pages={308 - 313} }