PCNS: a novel protocadherin required for cranial neural crest migration and somite morphogenesis in Xenopus.

@article{Rangarajan2006PCNSAN,
  title={PCNS: a novel protocadherin required for cranial neural crest migration and somite morphogenesis in Xenopus.},
  author={Janaki Rangarajan and Ting Luo and T. D. Sargent},
  journal={Developmental biology},
  year={2006},
  volume={295 1},
  pages={206-18}
}
Protocadherins (Pcdhs), a major subfamily of cadherins, play an important role in specific intercellular interactions in development. These molecules are characterized by their unique extracellular domain (EC) with more than 5 cadherin-like repeats, a transmembrane domain (TM) and a variable cytoplasmic domain. PCNS (Protocadherin in Neural crest and Somites), a novel Pcdh in Xenopus, is initially expressed in the mesoderm during gastrulation, followed by expression in the cranial neural crest… CONTINUE READING

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