PCGEM1, a prostate-specific gene, is overexpressed in prostate cancer.

  title={PCGEM1, a prostate-specific gene, is overexpressed in prostate cancer.},
  author={Vasantha Srikantan and Zhiqiang Zou and Gyorgy Petrovics and Liang Xu and Meena Augustus and Luther Davis and Jeffrey Livezey and Theresa Connell and Isabell A. Sesterhenn and Koichiro Yoshino and Gregory S. Buzard and Fathollah K Mostofi and David G. Mcleod and Judd W. Moul and Shiv Srivastava},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={97 22},
A prostate-specific gene, PCGEM1, was identified by differential display analysis of paired normal and prostate cancer tissues. Multiple tissue Northern blot analysis revealed that PCGEM1 was expressed exclusively in human prostate tissue. Analysis of PCGEM1 expression in matched normal and primary tumor specimens revealed tumor-associated overexpression in 84% of patients with prostate cancer by in situ hybridization assay and in 56% of patients by reverse transcription-PCR assay. Among… CONTINUE READING
126 Citations
1 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 126 extracted citations


Publications referenced by this paper.

Cytogenetics Nomenclature, ed

  • K. Heselmeyer, M. Macville, +5 authors T. Ried
  • J. Urol
  • 1992

Similar Papers

Loading similar papers…