PCEP enhances IgA mucosal immune responses in mice following different immunization routes with influenza virus antigens

@inproceedings{Eng2010PCEPEI,
  title={PCEP enhances IgA mucosal immune responses in mice following different immunization routes with influenza virus antigens},
  author={Nelson F. Eng and Srinivas Garlapati and Volker Gerdts and Lorne A. Babiuk and George K. Mutwiri},
  booktitle={Journal of immune based therapies and vaccines},
  year={2010}
}
BACKGROUND We previously demonstrated that polyphosphazenes, particularly PCEP, enhance immune responses in mice immunized subcutaneously and intranasally. The objective of the present study was to investigate the efficacy of polyphosphazenes as adjuvants when delivered through different routes of vaccine administration. METHODS BALB/c mice were immunized through intranasal, subcutaneous, oral and intrarectal delivery with vaccine formulations containing either influenza X:31 antigen alone or… CONTINUE READING

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