PBMCs reflect the immune component of the WAT transcriptome--implications as biomarkers of metabolic health in the postprandial state.

@article{OGrada2014PBMCsRT,
  title={PBMCs reflect the immune component of the WAT transcriptome--implications as biomarkers of metabolic health in the postprandial state.},
  author={Colm M O'Grada and Melissa J. Morine and Ciara Morris and Miriam F. Ryan and Eug{\`e}ne T Dillon and Marianne C Walsh and Eileen R Gibney and Lorraine Brennan and Michael J Gibney and Helen M. Roche},
  journal={Molecular nutrition & food research},
  year={2014},
  volume={58 4},
  pages={808-20}
}
SCOPE Food and nutrition studies often require accessing metabolically active tissues, including adipose tissue. This can involve invasive biopsy procedures that can be a limiting factor in study design. In contrast, peripheral blood mononuclear cells (PBMCs) are a population of circulating immune cells that are easily accessible through venipuncture. As transcriptomics is of growing importance in food and metabolism research, understanding the transcriptomic relationship between these tissue… CONTINUE READING

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