PAX8-PPARgamma rearrangement is frequently detected in the follicular variant of papillary thyroid carcinoma.

@article{Castro2006PAX8PPARgammaRI,
  title={PAX8-PPARgamma rearrangement is frequently detected in the follicular variant of papillary thyroid carcinoma.},
  author={Patricia Miranda Castro and Ana Paula Rebocho and Renato Jos{\'e} Soares and Jo{\~a}o Em{\'i}lio de Souza Magalh{\~a}es and L. Ginesta Roque and V{\'i}tor Trovisco and In{\^e}s Vieira de Castro and M. Cardoso-de-Oliveira and Elsa S. R. Fonseca and Paula Soares and Manuel Sobrinho-Sim{\~o}es},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2006},
  volume={91 1},
  pages={213-20}
}
CONTEXT The clinicopathological characteristics and the molecular features of the follicular variant of papillary thyroid carcinoma (FVPTC) remain controversial. OBJECTIVE/DESIGN/PATIENTS In an attempt to clarify such controversies and to find whether or not FVPTC cases share the molecular features of follicular tumors, we searched for the presence of PAX8-PPARgamma rearrangements, RAS mutations, and RAP-1, RAF-1, and BRAF mutations in a series of 40 FVPTCs as well as in 27 follicular thyroid… CONTINUE READING

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