PAX3+ skeletal muscle satellite cells retain long‐term self‐renewal and proliferation

@article{Yang2016PAX3SM,
  title={PAX3+ skeletal muscle satellite cells retain long‐term self‐renewal and proliferation},
  author={Qiumei Yang and J. Yu and B. Yu and Z. Huang and K. Zhang and De Wu and Jun He and X. Mao and P. Zheng and Daiwen Chen},
  journal={Muscle \& Nerve},
  year={2016},
  volume={54}
}
Introduction: Different populations of satellite cells (SCs) have been identified, but their functional difference remains unclear. Methods: We used cell‐surface markers and paired box transcription factor 3 (Pax3)/paired box transcription factor 7 (Pax7) expression to separate SC populations. In addition, self‐renewal, proliferation, and differentiation abilities of each population were analyzed. Results: Pax3+/Pax7‐ SCs exhibited higher proliferation ability characterized by forming clusters… Expand

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