PAX2 maintains the differentiation of mouse oviductal epithelium and inhibits the transition to a stem cell-like state


Recent studies have provided evidence that the secretory cells of the fallopian tube (oviduct) are a probable origin for high-grade serous ovarian carcinoma. In addition to secretory cells, the fallopian tube epithelium consists of ciliated cells and CD44+ undifferentiated stem-like cells. Loss of PAX2 expression is recognized as an early event in… (More)
DOI: 10.18632/oncotarget.20173


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