PAX2 and PAX8 expression in primary and metastatic renal tumors: a comprehensive comparison.

@article{Ozcan2012PAX2AP,
  title={PAX2 and PAX8 expression in primary and metastatic renal tumors: a comprehensive comparison.},
  author={Ayhan Ozcan and Gustavo de la Roza and Jae Yoon Ro and Steven R. S. Shen and Luan Truong},
  journal={Archives of pathology & laboratory medicine},
  year={2012},
  volume={136 12},
  pages={1541-51}
}
CONTEXT The diagnosis of renal cell carcinoma (RCC) remains problematic, especially in the context of metastasis or small-needle biopsies. PAX2 and PAX8 transcription factors are known to be expressed by several histologic types of renal neoplasms. OBJECTIVE To evaluate the diagnostic utility of PAX2 and PAX8 relative to one another, which has not been studied. DESIGN Consecutive tissue sections from the archival samples of 243 primary and 99 metastatic renal neoplasms were submitted to… CONTINUE READING
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