PATZ1 is a new prognostic marker of glioblastoma associated with the stem-like phenotype and enriched in the proneural subtype

@inproceedings{Guadagno2017PATZ1IA,
  title={PATZ1 is a new prognostic marker of glioblastoma associated with the stem-like phenotype and enriched in the proneural subtype},
  author={Elia Guadagno and Michela Vitiello and Paola Francesca and G. Cal{\'i} and Federica Caponnetto and Daniela Cesselli and Simona Camorani and Giorgio Borrelli and Marialuisa Califano and Paolo Cappabianca and Claudio Arra and Elvira Crescenzi and Laura Cerchia and Maria Laura del Basso De Caro and Monica Fedele},
  booktitle={Oncotarget},
  year={2017}
}
Glioblastoma (GBM), the most malignant of the brain tumors, has been classified on the basis of molecular signature into four subtypes: classical, mesenchymal, proneural and neural, among which the mesenchymal and proneural subtypes have the shortest and longest survival, respectively. Here we show that the transcription factor PATZ1 gene is upregulated in gliomas compared to normal brain and, among GBMs, is particularly enriched in the proneural subtype and co-localize with stemness markers… CONTINUE READING
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