PATERNAL AGE AND THE RISK OF BIRTH DEFECTS IN OFFSPRING

@article{McIntosh1995PATERNALAA,
  title={PATERNAL AGE AND THE RISK OF BIRTH DEFECTS IN OFFSPRING},
  author={G. McIntosh and A. Olshan and P. Baird},
  journal={Epidemiology},
  year={1995},
  volume={6},
  pages={282–288}
}
  • G. McIntosh, A. Olshan, P. Baird
  • Published 1995
  • Biology, Medicine
  • Epidemiology
  • Previous studies have shown that advanced paternal age is associated with an increase in new dominant mutations that may result in some rare congenital anomalies or syndromes in the offspring. Nevertheless, few epidemiologic studies have evaluated the effect of paternal age on the risk of more common birth defects. We examined data from the British Columbia Health Surveillance Registry, which included a total of 9,660 cases of birth defects (22 specific defect groups). We chose matched controls… CONTINUE READING
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