PASTA: splice junction identification from RNA-Sequencing data

  title={PASTA: splice junction identification from RNA-Sequencing data},
  author={Shaojun Tang and Alberto Riva},
  booktitle={BMC Bioinformatics},
Next generation transcriptome sequencing (RNA-Seq) is emerging as a powerful experimental tool for the study of alternative splicing and its regulation, but requires ad-hoc analysis methods and tools. PASTA (Patterned Alignments for Splicing and Transcriptome Analysis) is a splice junction detection algorithm specifically designed for RNA-Seq data, relying on a highly accurate alignment strategy and on a combination of heuristic and statistical methods to identify exon-intron junctions with… CONTINUE READING
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